Compounds and methods for inhibiting the interaction of bcl...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 261/02 (2006.01) A61K 31/4155 (2006.01) A61P 35/00 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2669596

One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit BcI function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

Un aspect de la présente invention concerne des composés hétérocycliques qui lient les protéines Bcl et inhibent la fonction BcI. Un autre aspect de la présente invention concerne des compositions comprenant un composé hétérocyclique selon l'invention. La présente invention concerne des procédés de traitement et de modulation des troubles associés à l'hyperprolifération, tels que le cancer.

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