C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/02 (2006.01) A61K 31/422 (2006.01) A61P 35/00 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2661166
The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit BcI function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
La présente invention concerne des composés contenant de l'isoxazolidine, qui se lient aux protéines Bcl et inhibent la fonction des Bcl. Les composés peuvent être utilisés pour traiter et moduler des troubles associés à une hyperprolifération, tels que le cancer.
Castro Alfredo C.
Depew Kristopher M.
Grogan Michael J.
Holson Edward B.
Hopkins Brian T.
Infinity Discovery Inc.
Smart & Biggar
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