Compounds and methods for modulating cadherin-mediated...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/435 (2006.01) A61K 38/03 (2006.01) A61K 38/17 (2006.01) C07K 4/12 (2006.01)

Patent

CA 2606227

Peptides comprising a cadherin cell adhesion recognition (CAR) sequence, and compositions comprising such peptides, are provided. Methods of using such peptides for modulating cadherin-mediated processes in a variety of therapeutic contexts are also provided. Methods are also provided for identifying compounds that are capable of modulating cadherin-mediated processes.

L'invention concerne des peptides comprenant une séquence (CAR) de reconnaissance de l'adhésion cellulaire médiée par la cadhérine et des compositions comprenant ces peptides. L'invention concerne également des méthodes permettant d'utiliser ces peptides pour moduler les processus médiés par la cadhérine dans divers contextes thérapeutiques. L'invention concerne également des méthodes permettant d'identifier des composés capables de moduler les processus médiés par la cadhérine.

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