Compounds and methods for modulating cell adhesion

Details Compounds and methods for modulating cell adhesion Compounds and methods for modulating cell adhesion

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/08 (2006.01) A61K 38/12 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 7/06 (2006.01) C07K 7/54 (2006.01) C07K 7/56 (2006.01) C07K 7/64 (2006.01) C07K 17/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2259966

Cyclic peptides and compositions comprising such cyclic peptides are provided. The cyclic peptides comprise a cadherin cell adhesion recognition sequence HAV. Methods for using such peptides and compositions for modulating cadherin- mediated cell adhesion in a variety of contexts are also provided.

Peptides cycliques et compositions comprenant de tels peptides cycliques. Les peptides cycliques comprennent une séquence de reconnaissance CAD (Cadherin Cell Adhesion) de type HAV (His-Ala-Val). Procédés d'utilisation de tels peptides et composés pour la modulation de l'adhérence cellulaire par CAD dans divers contextes.

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