Compounds and methods for modulating rho gtpases

Details Compounds and methods for modulating rho gtpases Compounds and methods for modulating rho gtpases

C - Chemistry, Metallurgy

07

D

C07D 217/10 (2006.01) A61K 31/4375 (2006.01) A61K 31/47 (2006.01) A61K 31/472 (2006.01) A61K 31/473 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01) C07D 217/12 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01) C07D 217/18 (2006.01) C07D 217/20 (2006.01)

Patent

CA 2692485

The present invention relates to methods and compositions that affect the GTP- binding activity of members of the Rho family GTPases, preferably Rac GTPases (Rac1, Rac1b, Rac2 and/or Rac3).

La présente invention concerne des procédés et des compositions qui affectent l'activité de liaison au GTP d'éléments des GTPases de la famille des Rho, en particulier les GTPases Rac (Rac1, Rac1b, Rac2 et/ou Rac3).

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