Compounds and methods for prevention and treatment of...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/06 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2398102

Compounds and compositions for eliciting or enhancing immune reactivity to HER- 2/neu protein are disclosed. The compounds include antigen-presenting cells, such as dendritic cells, which may be used for the prevention or treatment of malignancies in which the HER-2/neu oncogene is associated.

L'invention concerne des composés et compositions destinés à déclencher ou promouvoir une réactivité immune à la protéine HER-2/neu. Ces composés comprennent des cellules d'apport d'antigènes, telles que des cellules dendritiques, que l'on peut utiliser pour prévenir ou traiter des malignités auxquelles l'oncogène HER-2/neu est associé.

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