Compounds and methods for synthesis and purification of...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/02 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2671351

The present invention provides methods of extending nucleic acids and purifying target nucleic acids. The methods include the use of capping reagents to effect chain termination and provide a handle for purification via fluorous affinity methods.

La présente invention concerne des procédés d'extension d'acides nucléiques et de purification d'acides nucléiques cibles. Les procédés comprennent l'utilisation de réactifs de greffage pour réaliser des terminaisons de chaînes et fournir des terminaisons d'affinité pour permettre la purification par des procédés d'affinité du fluor.

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