Compounds and methods for the treatment of cancer

Details Compounds and methods for the treatment of cancer Compounds and methods for the treatment of cancer

C - Chemistry, Metallurgy

07

F

C07F 9/72 (2006.01) A61K 31/285 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2705467

The present invention provides methods of synthesizing organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.

La présente invention concerne des procédés de synthèse d'arsenicaux organiques. Plusieurs de ces composés possèdent une puissante activité cytotoxique in vitro contre de nombreuses lignées de cellules tumorales humaines, à la fois solides et d'origine hématologique, ainsi que contre des cellules sanguines malignes chez des patients atteints de leucémie.

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