Compounds and methods for the treatment or prevention of...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/40 (2006.01) A61K 31/381 (2006.01) A61P 31/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2607359

Compounds represented by formula (I) : or pharmaceutically acceptable salts and solvates thereof, wherein R1, X, Y, Y1, and Z are as defined herein, are useful for treating flavivi.pi.dae viral infections Said viral infection is Hepatitis C virus (HCV), bovme viral diarrhea virus (BVDV), hog cholera virus, dengue fever virus, Japanese encephalitis virus or yellow fever virus

Les composés de formule (I) : ou les sels et les solvates de qualité pharmaceutique desdits composés, où R1, X, Y, Y1 et Z sont tels que définis dans la description de l'invention, peuvent être employés pour le traitement d'infections virales par un flavivirus. Ladite infection virale appartient au groupe constitué par le virus de l'hépatite C (VHC), le virus de la diarrhée virale bovine (BVDV), le virus du choléra ovin, le virus de la dengue, le virus de l'encéphalite japonaise et le virus de la fièvre jaune.

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