Compounds and methods for treatment of thromboembolic disorders

Details Compounds and methods for treatment of thromboembolic disorders Compounds and methods for treatment of thromboembolic disorders

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) A61K 38/49 (2006.01) C12N 9/72 (2006.01) G06F 15/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2071145

X-7878 Abstract The present invention provides adducts of human t-PA derivatives, wherein said adducts comprise a t-PA derivative that lacks the Finger, Growth Factor and Kringle 1 domains, bound to an amphipathic molecule. The invention also provides methods for preparing said adducts and compositions for the treatment of thromboembolic disorders.

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