Compounds and methods of use

Details Compounds and methods of use Compounds and methods of use

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) A61K 31/47 (2006.01) C07D 215/233 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 491/10 (2006.01) C07D 493/04 (2006.01) C07D 493/10 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2740746

The present invention provides novel compounds useful in modulating the protein tyrosine kinase activity, and in modulating inter- and/or intra-cellular signaling. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

La présente invention porte sur de nouveaux composés utiles dans la modulation de l'activité protéine tyrosine kinase et dans la modulation d'une signalisation inter- et/ou intracellulaire. L'invention porte également sur des compositions pharmaceutiquement acceptables comprenant de tels composés et sur des procédés d'utilisation des compositions dans le traitement de troubles hyperprolifératifs chez les mammifères, notamment les êtres humains.

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