Compounds and methods of use to treat infectious diseases

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/48 (2006.01) A61K 31/155 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07C 279/16 (2006.01) C07C 279/18 (2006.01) C07C 279/26 (2006.01) C07D 239/50 (2006.01) C07D 251/14 (2006.01) C07D 251/48 (2006.01) C07D 473/34 (2006.01)

Patent

CA 2218561

The present invention concerns compounds that possess anti-infective activity. The invention encompasses methods of use of such compounds for treatment or prevention of infectious diseases, such as parasitic and viral diseases, including, for example, malaria and acquired immunodeficiency syndrome. The use of the compounds to detect certain specific protein structures which are present in nuclear localization sequences is also taught.

La présente invention concerne des composés présentant une activité anti-infectieuse ainsi que des procédés d'utilisation de ces composés pour le traitement ou la prévention des maladies infectieuses telles que les maladies virales et les parasitoses, y compris, notamment, le paludisme et le syndrome de l'immunodéficience acquise. L'utilisation de ces composés pour détecter certaines structures protéiques spécifiques présentes dans des séquences de localisation nucléaires est également décrite.

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