Compounds and pharmaceutical compositions as cathepsin s...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/82 (2006.01) A61K 31/381 (2006.01) A61K 31/455 (2006.01) A61K 31/47 (2006.01) A61K 31/4965 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61P 19/02 (2006.01) A61P 33/06 (2006.01) C07C 317/28 (2006.01) C07C 317/48 (2006.01) C07C 317/50 (2006.01) C07C 323/65 (2006.01) C07D 209/08 (2006.01) C07D 211/66 (2006.01) C07D 213/81 (2006.01) C07D 213/89 (2006.01) C07D 215/48 (2006.01) C07D 215/54 (2006.01) C07D 241/24 (2006.01) C07D 295/185 (2006.01) C07D 295/20 (2006.01) C07D 295/205 (2006.01) C07D

Patent

CA 2384974

The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

La présente invention concerne de nouveaux inhibiteurs sélectifs de la cathepsine S, leurs sels N-oxydes pharmaceutiquement acceptables, leurs utilisations comme agents thérapeutiques, et des méthodes se rapportant à leur production.

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