Compounds and pharmaceutical compositions for the treatment...

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6558 (2006.01) A61K 31/675 (2006.01) A61K 31/685 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07F 9/24 (2006.01) C07F 9/44 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2673776

Provided herein are compounds, compositions and methods for the treatment of liver disorders, including liver cancer and metabolic diseases, such as diabetes, hyperlipidemia, atherosclerosis, and obesity. Specifically, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-cancer agents.

L'invention concerne des composés, des compositions et des méthodes de traitement des troubles hépatiques, notamment du cancer du foie et des maladies métaboliques telles que le diabète, l'hyperlipidémie, l'athérosclérose et l'obésité. L'invention concerne en particulier des composés et des compositions de dérivés de nucléosides pouvant être administrés seuls ou associés à d'autres agents anticancéreux.

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