Compounds as ccri antagonists

Details Compounds as ccri antagonists Compounds as ccri antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01) A61K 31/4995 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2559917

A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein the symbols have meaning as defined, which are antagonists of CCR-1 and which find use pharmaceutically for treatment of diseases and conditions in which CCR-1 is implicated, e.g. inflammatory diseases.

L'invention concerne un composé de formule (I), y compris un sel ou un ester pharmaceutiquement acceptable correspondant. Les symboles de la formule ont l'acception définie dans la description. Ce type de composé, antagoniste vis-à-vis du CCR-1, est utilisable dans les applications pharmaceutiques pour le traitement des maladies et des affections faisant intervenir le CCR-1, par exemple en liaison avec les maladies inflammatoires.

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