C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/227
C07H 7/04 (2006.01) C07H 15/203 (2006.01)
Patent
CA 1181745
ABSTRACT The present invention relates to the benzoyl- and .alpha. -hydroxybenzyl-phenyl-oside derivatives of general formula: Image (I) [in which Z is CO or CHOH, X1, X2, X3, X4 and X5, which are identical or different, each represent an atom of hydrogen, an atom of halogen, an alkyl group with 1 to 4 carbon atoms, an alkyl group with 1 to 4 carbon atoms substituted by one or more atoms of halogen, an OH group, an alkoxy group with 1 to 4 carbon atoms, an alkoxy group with 1 to 4 carbon atoms substituted by one or more halogen atoms, a nitro group, a cyano group, a thiocyano group, an isothiocyano group, a NR'R'' group (where R' and R'', identical or different, each represent an atom of hydrogen or an alkyl group with 1 to 4 carbon atoms) X1 further being able to represent an -NH-CS-O-CH3 group or an -O-C-(CH3)2CO-R''' group (where R''' is an alkyl group with 1 to 4 carbon atoms and, preferably, an isopropyl group); and R represents a radical ose (the hydroxyl and amine functions of the radical ose being able to be substituted by acyl, alkyl or sulfate groups)], and to their diastereoisomers. It also relates to the method of preparation of these derivatives and to their application in therapeutics.
389050
Sim & Mcburney
Societe de Recherches Industrielles S.o.r.i.
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