Compounds capable of activating cholinergic receptors

Details Compounds capable of activating cholinergic receptors Compounds capable of activating cholinergic receptors

C - Chemistry, Metallurgy

07

D

C07D 213/38 (2006.01) A61K 31/137 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61P 25/28 (2006.01) C07D 239/26 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2501335

The present invention generally relates to nicotinic compounds, in the form of aryl substituted olefinic compounds, as well as pro-drug, N-oxide, metabolite and pharmaceutically acceptable salt forms thereof. Methods of modulating neurotransmitter release via administration of the compounds, pro-drugs, N- oxides and/or pharmaceutically acceptable salts are also disclosed.

L'invention concerne généralement des composés nicotiniques, sous la forme de composés oléfiniques aryle substitués, et un promédicament, un N-oxyde, un métabolite et des formes de sels pharmaceutiquement acceptables de ceux-ci. L'invention concerne également des méthodes de modulation de la libération de neurotransmetteur consistant à administrer les composés, les promédicaments, les N-oxydes et/ou les sels pharmaceutiquement acceptables décrits dans l'invention.

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