Compounds, compositions and methods for the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 249/08 (2006.01) A61K 31/415 (2006.01) A61K 31/4164 (2006.01) A61K 31/4196 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C07D 231/12 (2006.01) C07D 233/64 (2006.01)

Patent

CA 2735120

Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of .beta.-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.

L'invention porte sur des composés de dihydroxyaryle et sur des esters pharmaceutiquement acceptables, sur leur synthèse, sur des compositions pharmaceutiques les contenant, et sur leur utilisation dans le traitement de maladies de la ß-amyloïde, telle que l'on peut en observer dans la maladie d'Alzheimer, et de synucléinopathies, telle que l'on peut en observer dans la maladie de Parkinson, et sur la fabrication de médicaments pour un tel traitement.

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