C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 251/70 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 251/18 (2006.01)
Patent
CA 2684968
We describe compounds of the following general formula (I): wherein X is fluorine or chlorine; Y is oxygen, sulfur, or an amino group; R is an amino, hydroxyl, sulfonamide, or carboxamide group or an N-monomethyl or N-dimethyl analog thereof; m is an integer from 2 to 6, and n is an integer from 0 to 2. The compounds may be used for treating certain cancers and autoimmune diseases.
L'invention porte sur des composés de la formule générale suivante (I) : dans laquelle X représente fluor ou chlore; Y représente oxygène, soufre ou un groupe amino; R représente un groupe amino, hydroxyle, sulfonamide ou carboxamide ou un analogue N-monométhylé ou N-diméthylé de ceux-ci; m est un entier de 2 à 6, et n est un entier de 0 à 2. Les composés peuvent être utilisés pour traiter certains cancers et certaines maladies auto-immunes.
Abbott Shaun D.
Gagnon Lyne
Geerts Lilianne
Grouix Brigitte
Penney Christopher
Leclaire France
Prometic Biosciences Inc.
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