Compounds comprising a cyclobutoxy group

Details Compounds comprising a cyclobutoxy group Compounds comprising a cyclobutoxy group

C - Chemistry, Metallurgy

07

D

C07D 211/38 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/5355 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) C07D 211/46 (2006.01) C07D 213/75 (2006.01) C07D 295/096 (2006.01) C07D 295/192 (2006.01)

Patent

CA 2723626

The present invention relates to compounds of formula (I) comprising a cyclobutoxy group, processes for preparing them, pharmaceutical compositions comprising said compounds and their use as pharmaceuticals, useful for the treatment and prevention of diseases or pathological conditions of the central nervous system including mild-cognitive impairments, Alzheimer's disease, learning and; memory disorders, cognitive disorders, attention deficit disorder, attention-deficit hyperactivity disorder, Parkinson's disease, schizophrenia, dementia, depression, epilepsy, seizures, convulsions, sleep/wake and arousal/vigilance disorders such as hypersomnia and narcolepsy, pain and/or obesity.

La présente invention concerne des composés de formule (I) comprenant un groupe cyclobutoxy, des procédés pour les préparer, des compositions pharmaceutiques comprenant lesdits composés et leur utilisation en tant quagents pharmaceutiques, le traitement et la prévention de maladies ou états pathologiques du système nerveux central comprenant des troubles cognitifs légers, la maladie dAlzheimer, des troubles de lapprentissage et de la mémoire, des troubles cognitifs, des troubles de déficit de lattention, un trouble dhyperactivité avec déficit de lattention, la maladie de Parkinson, la schizophrénie, la démence, la dépression, lépilepsie, les crises dépilepsie, les convulsions, les troubles de sommeil/réveil et déveil/vigilance tels que lhypersomnie et la narcolepsie, la douleur et/ou lobésité.

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