Compounds containing a n-heteroaryl moiety linked to fused...

Details Compounds containing a n-heteroaryl moiety linked to fused... Compounds containing a n-heteroaryl moiety linked to fused...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) C07D 239/00 (2006.01) C07D 249/00 (2006.01)

Patent

CA 2566917

The invention relates to compounds containing a N-heteroaryl moiety, which is linked via oxygen, sulfur or nitrogen, or via a methylene bridge and oxygen, sul~fur or nitrogen to a fused ring moiety, in particular to the 1,2,3- triazolo[4,5~d]pyrimidine-7-yl radical. The invention also relates to a process for the prepara~tion of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidases-related diseases and disorders and inhibition of platelet activation.

L'invention concerne des composés renfermant une fraction N-hétéroaryle liée par oxygène, soufre ou azote ou au moyen d'un pont méthylène et d'oxygène, de soufre ou d'azote à une fraction de noyau fusionnée, notamment au radical 1,2,3-triazolo[4,5-d]pyrimidine-7-yl. L'invention concerne également un procédé de préparation desdits composés et l'utilisation de ceux-ci dans des médicaments destinés au traitement de maladies et troubles relatifs aux NAD(P)H oxydases et à l'inhibition de l'activation des plaquettes.

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