C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/14 (2006.01) C07D 209/12 (2006.01) C07D 209/14 (2006.01) C07D 241/08 (2006.01) C07D 317/50 (2006.01)
Patent
CA 2738694
The present invention describes a series of derivatives of 2-(3- methylenedioxy)-benzoyl indol, their mixtures, their pharmaceutically acceptable salts, their enantiomers, pharmaceutical compositions comprising them, processes for preparing them, use in the prophylactic and/or curative treatment of sexual dysfunction. More specifically, the invention describes derivatives (R)-3-((2-(benzo[d][1,3]dioxol-5-carbonyl)-1H-indol-3-yl)methyl)-1- methylpiperazine-2,5-dione, and S)-3-((2-(benzo[d] [1,3]dioxol-5-carbonyl)-1H-indol-3-yl)methyl)-1-methylpiperazine-2,5-dione.
La présente invention concerne une série de dérivés de 2-(3-méthylènedioxy)-benzoyl-indole, leurs mélanges, leurs sels pharmaceutiquement acceptables, leurs énantiomères, des compositions pharmaceutiques les comprenant, des procédés permettant de les préparer, et leur utilisation dans le traitement prophylactique et/ou curatif de troubles sexuels. Plus spécifiquement, l'invention concerne des dérivés de (R)-3-((2-(benzo[d][1,3]dioxol-5-carbonyl)-1H-indol-3-yl)méthyl)-1-méthylpipérazine-2,5-dione, et de S)-3-((2-(benzo[d][1,3]dioxol-5-carbonyl)-1H-indol-3-yl)méthyl)-1-méthylpipérazine-2,5-dione.
Sacurai Sergio Luiz
Touzarim Carlos Eduardo Da Costa
Zaim Marcio Henrique
Biolab Sanus Farmaceutica Ltda.
Gowling Lafleur Henderson Llp
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