C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/037 (2006.01) A61K 31/222 (2006.01) A61K 31/427 (2006.01) A61K 38/06 (2006.01) A61P 39/06 (2006.01) C07D 277/06 (2006.01)
Patent
CA 2547086
Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which have the potential to express anti-oxidant activity capable of reducing reactive oxygen species in cells. These compounds may be used to inhibit oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.
Composés contenant des acides aminés ou des peptides uniques, ou des dérivés desdits acides et peptides, qui possèdent le potentiel d'exprimer une activité antioxydante capable de réduire les espèces oxygénées radicalaires dans les cellules. Ces composés peuvent être utilisés pour inhiber les lésions ou la mort cellulaires induites par le stress oxydatif à la fois in vivo et ex vivo. Des procédés de synthèse de ces composés sont également décrits.
Anders Marion W.
Sharma Virendra K.
Sheu Shey-Shing
Xu Lin
Borden Ladner Gervais Llp
University Of Rochester
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