Compounds for detection of infection by chlamydophila abortus

C - Chemistry – Metallurgy – 07 – K

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C07K 14/295 (2006.01) A61K 39/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2399135

The present invention relates to compounds having binding affinity for specific sub-populations of antibodies to Chlamydophila abortus. More particularly, this invention relates to the use of compounds for the detection of Chlamydophila abortus infection. The proposed compound sequences provide unique reagents for the detection of sub-populations of antibodies to Chlamydophila abortus with supreme specificity with regard to possible cross- reactions with Chlamydophila pecorum and Chlamydophila psittaci in animals, such as sheep, goats and cattle, and Chlamydia trachomatis and Chlamydia pneumoniae in man.

L'invention concerne des composés possédant une affinité de liaison pour des sous-populations d'anticorps dirigés contre Chlamydophila abortus. Cette invention concerne, plus particulièrement, l'utilisation de ces composés pour détecter une infection induite par Chlamydophila abortus. Les séquences de composés proposés fournissent des réactifs uniques pour détecter des sous-populations d'anticorps dirigés contre Chlamydophila abortus, possédant une très grande spécificité par rapport à des réactions croisées possibles avec Chlamydophila pecorum etChlamydophila psittaci chez des animaux, tels que les moutons, les chèvres, et le bétail, et Chlamydia trochomatis et Chlamydia pneumoniae chez l'homme.

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