Compounds for immunopotentiation

Details Compounds for immunopotentiation Compounds for immunopotentiation

A - Human Necessities

61

K

A61K 31/517 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2571421

Methods of stimulating an immune response and treating patients responsive thereto with 3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-diones, staurosporine analogs, derivatized pyridazines, chromen-4-ones, indolinones, quinazolines, nucleoside analogs, and other small molecules are disclosed. In a preferred embodiment benzopyrimidine derivatives such as ZD-6474, MLN-518, lapatinib, gefitinib or erlotinib are used.

La présente invention concerne des méthodes utiles pour stimuler une réponse immunitaire et pour traiter des patients qui y réagissent, avec des 3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-diones, des analogues de staurosporine, des pyridazines dérivées, des chromen-4-ones, des indolinones, des quinazolines, des analogues de nucléoside et d'autres petites molécules.

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