Compounds for inflammation and immune-related uses

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/12 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 405/14 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2595855

The invention relates to compounds of structural formula (I) and structural formula (Vl): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R, R1, R2, Z, L, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

L'invention concerne des composés de formule structurelle (I) et de formule structurelle (Vl), ou un sel, un solvate, un clathrate, ou un promédicament pharmaceutiquement acceptables desdits composés. Dans lesdites formules R, R1, R2, Z, L et n sont tels que définis dans l'invention. Lesdits composés sont utiles en tant qu'agents immunosuppresseurs ainsi que pour le traitement et la prévention d'états inflammatoires, de troubles allergiques et de troubles immunitaires.

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