Compounds for inhibiting beta-amyloid peptide release and/or...

Details Compounds for inhibiting beta-amyloid peptide release and/or... Compounds for inhibiting beta-amyloid peptide release and/or...

C - Chemistry, Metallurgy

07

D

C07D 243/24 (2006.01) A61K 31/55 (2006.01) C07D 221/00 (2006.01) C07D 221/22 (2006.01) C07D 223/00 (2006.01) C07D 223/18 (2006.01) C07D 243/12 (2006.01) C07D 243/14 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01) C07D 471/06 (2006.01)

Patent

CA 2325388

Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

L'invention concerne des composés qui inhibent la libération et/ou la synthèse de peptide bêta-amyloïde et qui, de ce fait, sont utiles dans le traitement de la maladie d'Alzheimer. L'invention concerne également des compositions renfermant un composé qui inhibe la libération et/ou la synthèse de peptide bêta-amyloïde, ainsi que des procédés relatifs au traitement de la maladie d'Alzheimer par le biais desdites compositions, à des fins prophylactiques et thérapeutiques.

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