A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01) A61K 31/16 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61K 31/18 (2006.01) A61K 31/198 (2006.01) A61K 31/401 (2006.01) A61K 31/404 (2006.01) A61K 31/405 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) C07C 259/00 (2006.01)
Patent
CA 2575928
This invention is directed to inhibitors of copper-containing amine oxidases (E.C.1.4.3.6) including semicarbazide-sensitive amine oxidase (SSAO; also known as vascular adhesion protein- 1, VAP-I), and their therapeutic use in inflammatory diseases, diabetes and its associated complications, atherosclerosis, neurodegenerative diseases, obesity, hypertension and cancer.
L'invention concerne des inhibiteurs d'amine oxydases contenant du cuivre (E.C.1.4.3.6) y compris l'amine oxydase sensible au semi-carbazide (SSAO; que l'on appelle aussi protéine 1 d'adhésion vasculaire, VAP-I), et leur utilisation thérapeutique pour les maladies inflammatoires, le diabète et ses complications associées, l'athérosclérose, les maladies neurodégénératives, l'obésité, l'hypertension et le cancer.
Albericio Palomera Fernando
Clauzel Luc Marti
Exposito Miriam Royo
Font Francesc Yraola
Garcia-Vicente Silvia
Borden Ladner Gervais Llp
Genmedica Therapeutics Sl
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