Compounds for inhibiting mitotic progression

Details Compounds for inhibiting mitotic progression Compounds for inhibiting mitotic progression

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2669680

The present invention relates to compounds of formula (I) : and methods for the treatment of cancer. In particular, the invention provides potent inhibitors of Aurora A kinase, pharmaceutical compositions comprising the compounds, and methods of using the compounds for the treatment of cancer.

La présente invention concerne des composés représentés par la formule générale (I), ainsi que des procédés destinés au traitement du cancer. L'invention concerne plus particulièrement de puissants inhibiteurs de la kinase Aurora A, des compositions pharmaceutiques comprenant les composés, ainsi que des procédés d'utilisation de ces composés pour le traitement du cancer.

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