Compounds for nonsense suppression, and methods for their use

F - Mech Eng,Light,Heat,Weapons – 28 – G

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F28G 3/10 (2006.01)

Patent

CA 2583159

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

La présente invention concerne des procédés, des composés et des compositions destinés au traitement ou à la prévention des maladies associées aux mutations non-sens dans un ARNm par l'administration de composés ou compositions de la présente invention. L'invention concerne plus particulièrement des procédés, composés et compositions destinés à supprimer la terminaison prématurée de la traduction, associée à une mutation non-sens dans un ARNm.

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