C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/04 (2006.01) A61K 31/42 (2006.01) A61K 31/423 (2006.01) A61K 31/4245 (2006.01) A61K 31/4439 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 263/57 (2006.01) C07D 413/10 (2006.01) C07D 498/20 (2006.01)
Patent
CA 2582885
The present invention relates to compounds, compositions and their use for the manfacture of midicament for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
L'invention concerne des procédés, composés et compositions permettant de traiter ou prévenir des maladies associées à des mutations non-sens dans un ARNm, par administration de composés ou compositions de cette invention. Plus spécifiquement, l'invention concerne des procédés, composés et compositions permettant de supprimer la terminaison prématurée de traduction associée à une mutation non-sens dans un ARNm.
Karp Gary M.
Welch Ellen
Wilde Richard
Mbm Intellectual Property Law Llp
Ptc Therapeutics Inc.
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