A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/675 (2006.01) C07F 9/59 (2006.01) C07F 9/6553 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2550352
The present invention is related to compounds having formula (I), wherein the dashed line indicates a single or double bond or is absent and wherein A1-A9, Q, R1-R11, T, U, V, W1-W3, X1, X2, Y and Z are as defined in the claims and description, pharmaceutical compositions comprising the compounds and the use of the compounds for the manufacture of a medicament for the treatment of deseases involving abnormal cell proliferation, undesired cell proliferation, abnormal mitosis and/or undesired mitosis.
La présente invention a trait à des composés de formule (I), dans laquelle les lignes en pointillé représentent une liaison simple ou double et dans laquelle A?1¿-A?9¿, Q, R?1¿-R?11¿, T, U, V, W?1¿-W?3¿, X?1¿, X?2¿, Y et Z sont tels que définis dans les revendications et la description, à des compositions pharmaceutiques comportant les composés et à l'utilisation des composés pour la fabrication d'un médicament pour le traitement de maladies impliquant une prolifération cellulaire anormale, une prolifération cellulaire indésirable, une mitose anormale et/ou une mitose indésirable.
Christner Claudia
Gibson Christoph
Hummel Gerd
Jobron Laurence
Knolle Jochen
Borden Ladner Gervais Llp
Jerini Ag
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