Compounds for the prevention and treatment of cardiovascular...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/91 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) C07D 403/02 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2747417

Disclosed are novel compounds that are useful for regulating the expression of apolipoprotein A-I (ApoA-1), and their use for the treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis. Also disclosed are pharmaceutical compositions comprising the novel compounds.

La présente invention concerne de nouveaux composés utiles dans la régulation de l'expression de l'apolipoprotéine A-I (ApoA-l), et leur utilisation pour le traitement et la prévention de maladies cardiovasculaires et états pathologiques associés, parmi lesquels les troubles liés au cholestérol ou aux lipides, comme par exemple l'athérosclérose. L'invention concerne également des compositions pharmaceutiques comprenant les nouveaux composés.

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