C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/78 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/382 (2006.01) A61P 25/28 (2006.01) C07C 311/18 (2006.01) C07D 335/06 (2006.01)
Patent
CA 2500109
The invention relates to compounds of formula (I). Useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
La présente invention concerne des composés de formule (I) qui sont utiles pour traiter la maladie d'Alzheimer et d'autres maladies similaires. Ces composés comprennent des inhibiteurs de l'enzyme bêta-secrétase qui sont utiles pour traiter la maladie d'Alzheimer et d'autres maladies similaires qui se caractérisent par le dépôt du peptide A bêta chez un mammifère. Les composés de l'invention peuvent être utilisés dans des compositions pharmaceutiques et des procédés de traitement pour réduire la formation du peptide A bêta.
Hom Roy
John Varghese
Elan Pharmaceuticals Inc.
Hom Roy
John Varghese
Osler Hoskin & Harcourt Llp
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