Compounds for the treatment of cns and amyloid associated...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) C07D 215/12 (2006.01) C07D 233/42 (2006.01) C07D 233/54 (2006.01) C07D 235/04 (2006.01) C07D 257/04 (2006.01) C07D 263/30 (2006.01) C07D 271/07 (2006.01) C07D 295/04 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2586334

Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing CNS and amyloid associated disease. Also described are methods, compounds, pharmaceutical compositions and kits for detecting, diagnosing, monitoring and treating or preventing CNS and amyloid associated disease Pn particular, modified blood bram barrier (BBB) vectors such as phenylalanine derivatives are described as to provide parameters to select CNS drug candidates designated to penetrate the bram using a specific active transporter.

L'invention concerne des procédés, des composés, des compositions pharmaceutiques et des kits permettant de traiter ou de prévenir des maladies associées au SNC et à la protéine amyloïde. L'invention concerne également des procédés, des composés, des compositions pharmaceutiques et des kits permettant de détecter, diagnostiquer, surveiller et traiter ou prévenir des maladies associées au SNC et à la protéine amyloïde.

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