Compounds for the treatment of demyelinating and autoimmune...

A - Human Necessities – 61 – K

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Details

A61K 31/675 (2006.01) A61K 31/185 (2006.01) A61K 31/53 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2534868

The invention relates to the treatment of autoimmune and demyelinating diseases and, in particular, the treatment of multiple sclerosis. The treatment consists of the administration of P2X purinergic receptor antagonists, which leads to a remission of the symptoms associated with said type of diseases. The aforementioned result has been demonstrated using both in vitro cell models and animal models.

La présente invention concerne le traitement de maladies démyélinisantes et auto-immunes et plus précisément le traitement de la sclérose en plaques. Ce traitement consiste à administrer des substances antagonistes des récepteurs purinergiques P2X, ce qui produit une rémission des symptômes caractéristiques de ce type de maladie. Ce résultat a été démontré sur des modèles cellulairesin vitro et animaux.

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