Compounds for the treatment of flaviviridae infections

Details Compounds for the treatment of flaviviridae infections Compounds for the treatment of flaviviridae infections

A - Human Necessities

61

K

A61K 31/7068 (2006.01) A61K 31/7056 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2529311

The disclosed invention is a composition for and a method of treating a Flaviviridae infections, such as bovine viral diarrhea virus (~BVDV~), Dengue Virus (DENV), West Nile Virus (WNV) and hepatitis C virus (HCV), as well as abnormal cellular proliferation, in a host, including animals, and especially humans, using a nucleoside of general formula (I) - (V) or N-(phosphonoacetyl)- L-aspartate (PALA), or a pharmaceutically acceptable salt or prodrug thereof.

Composition et procédé permettant de traiter, chez un hôte tel qu'un animal, et notamment chez l'homme, les infections par flavivirus, par exemple le virus de la diarrhée virale des bovins (BVDV), le virus de la dengue (DENV), le virus West Nile (MNV) et le virus de l'hépatite C (HCV), ainsi que la prolifération cellulaire anormale, et ce à l'aide d'un nucléoside répondant à la formule générale (I) (V) ou de N-(phosphonoacétyl)-L-aspartate (PALA), ou de son sel ou promédicament pharmaceutiquement acceptable.

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