Compounds for the treatment of urinary incontinence

Details Compounds for the treatment of urinary incontinence Compounds for the treatment of urinary incontinence

C - Chemistry, Metallurgy

07

C

167/232, 167/268

C07C 233/40 (2006.01) A61K 31/165 (2006.01) A61K 31/445 (2006.01) C07C 235/34 (2006.01) C07D 295/13 (2006.01)

Patent

CA 2001641

ABSTRACT The invention concerns compounds having the formula I Image (I) wherein Ar is a phenyl or benzyl group which is optionally substituted with hydroxy or alkoxy; R1 is hydrogen, lower alkyl, lower alkoxy, hydroxy; R2 is hydrogen, lower alkyl; R3 is NR4R5, wherein R4 and R5 which can be the same or different, are lower al- kyl, or wherein R4 and R5, when taken together, form a ring with the nitrogen atom, whereby said ring optionally is sub- stituted with lower alkyl; n is 0 or 1; m is 2 or 3 and their salts with physiologically acceptable acids and when the compounds can be in form of optical isomers, the racemic mixture and the individual isomers, for the treatment of dis- orders of the urinary bladder.

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