A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/575 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2565002
The present invention provides compositions and methods for treating and preventing Alzheimer's disease by administering to a subject an effective amount of a dammarane or ginsenoside compound. The invention also provides compositions and methods for modulating beta-amyloid protein production, including A.beta.42 in a cell. The invention further provides compositions and methods for treating and preventing neurodegeneration by administering to a subject an effective amount of a dammarane or ginsenoside compound. Additionally, the invention provides kits for use in treating and/or preventing Alzheimer's disease and neurodegeneration, as well as for reducing the production of beta-amyloid protein.
L'invention concerne des compositions et de méthodes de traitement et de prévention de la maladie d'Alzheimer par l'administration à un sujet d'une dose efficace d'un composé de dammarane ou de ginsenoside. L'invention porte également sur des compositions et des méthodes de modulation de la production de la protéine bêta-amyloïde, comportant Aß42 dans une cellule. Elle se rapporte encore à des compositions et à des méthodes de traitement et de prévention de la neurodégénérescence par l'administration à un sujet d'une dose efficace d'un composé de dammarane ou de ginsenoside. De plus, l'invention concerne des kits à utiliser dans le traitement et/ou la prévention de la maladie d'Alzheimer et de la neurodégénérescence ainsi que la réduction de la production de la protéine amyloïde bêta.
Chung Sungkwon Jeffrey
Kim Tae-Wan
Piasetzki Nenniger Kvas Llp
The Trustees Of Columbia University In The City Of New York
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