Compounds for treating angiogenesis

Details Compounds for treating angiogenesis Compounds for treating angiogenesis

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/416 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2530679

The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions.

La présente invention concerne des procédés et des compositions pharmaceutiques pour inhiber l'expression de gènes HIF et de gènes à régulation HIF, pour inhiber l'angiogenèse, provoquer l'arrêt du cycle cellulaire dans des cellules cancéreuses, et traiter des maladies ou des états pathologiques liées/liés à la prolifération cellulaire.

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