C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/04 (2006.01) A61K 31/4706 (2006.01) A61P 33/14 (2006.01)
Patent
CA 2743903
A compound, particularly an antimalarial compound, according to formula (I) or a pharmaceutically acceptable salt thereof, wherein: X is an electron-withdrawing group; A is an optionally substituted alkanediyl or an optionally substituted cycloalkanediyl that includes 2 to 5 carbon atoms; and R1 and R2 are each individually H, tert- butyl, isopropyl, or optionally substituted cycloalkyl.
La présente invention concerne un composé, en particulier un composé antipaludique, répondant à la formule (I), ou un sel pharmaceutiquement acceptable de celui-ci, dans lequel X représente un groupe de retrait d'électrons, A un groupe alcanediyle éventuellement substitué ou un groupe cycloalcanediyle éventuellement substitué qui porte 2 à 5 atomes de carbone, et R1 et R2 représentent chacun individuellement H ou un groupe tert-butyle, isopropyle, ou cycloalkyle éventuellement substitué.
Hinrichs David J.
Riscoe Michael K.
Winter Rolf W.
Oregon Health & Science University
Smart & Biggar
The Government Of The United States Of America D.b.a.the Departm
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