C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/86 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) C07C 243/24 (2006.01) C07C 327/00 (2006.01) C07D 207/416 (2006.01) C07D 231/08 (2006.01) C07D 237/04 (2006.01) C07D 277/50 (2006.01) C07D 303/48 (2006.01) C07D 307/66 (2006.01) C07D 307/68 (2006.01) C07D 309/30 (2006.01) C07D 333/36 (2006.01) C07D 333/38 (2006.01)
Patent
CA 2661440
Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also, disclosed are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier.
L'invention concerne des composés et des méthodes d'utilisation des composés décrits pour le traitement d'un sujet atteint d'un trouble prolifératif tel qu'un cancer, ainsi que des méthodes de traitement des troubles sensibles à l'induction de la protéine Hsp 70 et/ou à l'induction des cellules tueuses naturelles. L'invention concerne également des compositions pharmaceutiques contenant les composés décrits et un excipient pharmaceutiquement acceptable.
Chen Shoujun
Demko Zachary
Koya Keizo
Sun Lijun
Xia Zhi-Qiang
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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