Compounds for treating proliferative disorders

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 327/56 (2006.01) A61K 31/16 (2006.01) A61P 35/00 (2006.01) C07C 243/28 (2006.01) C07C 255/42 (2006.01) C07C 257/20 (2006.01) C07C 261/04 (2006.01) C07C 307/04 (2006.01) C07C 311/49 (2006.01) C07C 337/06 (2006.01) C07D 207/34 (2006.01) C07D 263/48 (2006.01) C07D 271/10 (2006.01) C07D 307/38 (2006.01) C07F 9/02 (2006.01)

Patent

CA 2660524

Disclosed are compounds of formulae (I), (III), (IV), (VII), (X), (XI), (XII), (XIII) and (XIV), wherein the variabables are as defined in the claims, and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also disclosed are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier.

L'invention concerne des composés et procédés d'utilisation des composés de l'invention pour traiter un sujet souffrant d'un trouble prolifératif, tel qu'un cancer, et des procédés servant à traiter des troubles sensibles à l'induction du gène Hsp70 et/ou à l'induction de cellules tueuses naturelles. L'invention concerne également des compositions pharmaceutiques comprenant les composés de l'invention et un véhicule acceptable du point de vue pharmaceutique.

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