Compounds for use in managing labour

A - Human Necessities – 61 – K

Patent

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A61K 31/18 (2006.01) A61K 31/54 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2183217

A method of substantially preventing or reducing at least one of the changes in the female reproductive system associated with the onset or continuation of labour the method comprising administering to the female an effective amount of a compound which selectively inhibits cyclo-oxygenase-2 (COX-2) function. A method of substantially preventing or reducing uterine contractility the method comprising administering to the female an effective amount of a compound which selectively inhibits cyclo-oxygenase-2 (COX-2) function. Preferably the compound is nimesulide.

Méthode pour prévenir ou réduire sensiblement au moins l'un des changements dans le système reproductif de la femelle, associés au début ou à la continuation du travail; la méthode consiste à administrer à la femelle une quantité efficace d'un composé provoquant l'inhibition sélective de la fonction de la cyclo-oxygénase-2 (COX-2). Méthode pour prévenir ou réduire sensiblement la contraction utérine; la méthode consiste à administrer à la femelle une quantité efficace d'un composé provoquant l'inhibition sélective de la fonction de la cyclo-oxygénase-2 (COX-2). Le composé est de préférence la nimésulide.

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