A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/498 (2006.01) A61K 31/137 (2006.01) A61K 31/4164 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2530938
In methods, compounds, and topical formulations for treatment of rosacea incorporating compounds represented by the formulas below: (I) wherein each of R1, R2, and R3 is independently hydrogen, hologen, alkyl, or alkoxy; each of R4 and R5 is independently hydrogen, alkyl, or alkoxy; and each of R6 and R7 is independently hydrogen, nitro, alkyl, or alkoxy; wherein each of A1, A3, and A4 is independently hydrogen or alkyl; and A2 is independently hydrogen or hydroxy; and wherein each of B1, B2, and B3 is independently hydrogen, hydroxy, or alkoxy; and each of B4 and B5 is independently hydrogen or alkyl, applying such compounds topically as sprays, mists, aerosols, solutions, lotions, gels, creams, ointments, pastes, unguents, emulsions, and suspensions to treat rosacea and its symptoms.
L'invention concerne des méthodes, des composés et des préparations locales pour le traitement de la rosacée, les composés représentés par les formules (I), (II) et (III) sont utilisés. Dans lesdites formules, R¿1?, R¿2?, et R¿3? représentent indépendamment hydrogène, halogène, alkyle ou alcoxy ; chaque R¿4? et R¿5? représente indépendamment hydrogène, alkyle ou alcoxy ; et chaque R¿6? et R¿7? représente indépendamment hydrogène, nitro ou alcoxy ; A¿1?, A¿3?, et A¿4? représentent chacun hydrogène ou alkyle, et A¿2? représente indépendamment hydrogène ou hydroxy ; et B¿1?, B¿2?, et B¿3? représentent indépendamment hydrogène, hydroxy ou alcoxy ; et B¿4? et B¿5? représentent chacun hydrogène ou alkyle. Ces composés sont appliqués localement sous forme de pulvérisations, brouillards, aérosols, solutions, lotions, gels, crèmes, onguents, pâtes, émulsions et suspensions pour le traitement de la rosacée et des ses symptômes.
Dejovin Jack
Rossi Thomas M.
Finlayson & Singlehurst
Galderma Pharma S.a.
Sansrosa Pharmaceutical Development Inc.
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