Compounds having anti-proliferative properties

A - Human Necessities – 61 – K

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A61K 31/665 (2006.01) A61K 31/355 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2513427

There is provided a method of inhibiting the occurrence of one of more of the following conditions: - the proliferation of monocytes/macrophages; or - the proliferation of smooth muscle cells; or - the expression of CD36 receptors; or - the uptake of oxidized LDL, the method comprising the step of administering an effective amount of one or more phosphate derivatives of one or more electron transfer agents.

L'invention concerne un procédé permettant d'inhiber l'apparition d'au moins une des conditions suivantes : - la prolifération de monocytes/macrophages ; ou la prolifération de cellules musculaires lisses ; ou l'expression des récepteurs CD36; ou l'absorption de LDL oxydé. Ce procédé consiste à administrer une quantité efficace d'au moins un dérivé de phosphate d'au moins un agent de transfert d'électrons.

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