C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/48 (2006.01) A61K 31/18 (2006.01) A61P 35/00 (2006.01) C07D 295/08 (2006.01)
Patent
CA 2680239
The invention relates to aryl-sulphonamido compounds endowed with inhibitory activity against metallo proteases MMP, having Formula (I) below wherein R, R 1, R 2, R 3, R 4, R 5, n and m have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them andto their use as therapeutic agents, particularly in the treatment ofdegenerative disorders.
Cette invention se rapporte à des composés arylsulfonamido pourvus d'une activité inhibitrice envers les métalloprotéases MMP, de formule (I) dans laquelle R, R 1, R 2, R 3, R 4, R 5, n et m ont la signification énoncée dans la description ; l'invention concerne également leur procédé de préparation, des compositions pharmaceutiques les contenant et leur utilisation en tant qu'agents thérapeutiques, en particulier dans le traitement des maladies dégénératives.
Balsamo Aldo
Nuti Elisa
Orlandini Elisabetta
Rossello Armando
Tuccinardi Tiziano
Bracco Imaging S.p.a.
Smart & Biggar
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