Compounds having crth2 antagonist activity

Details Compounds having crth2 antagonist activity Compounds having crth2 antagonist activity

C - Chemistry, Metallurgy

07

D

C07D 209/10 (2006.01) A61K 31/405 (2006.01)

Patent

CA 2658496

Compounds of general formula (I) wherein R is phenyl optionally substituted with one or more halo substituents ; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.

L'invention concerne des composés de formule générale (I), dans laquelle R représente un phényle éventuellement substitué par un ou plusieurs substituants halogène ; et leurs sels, hydrates, solvates, complexes ou promédicaments pharmaceutiquement acceptables, utiles dans des compositions administrables par voie orale pour le traitement de maladies allergiques telles que l'asthme, la rhinite allergique et la dermatite atopique.

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