Compounds having lectin properties and biological uses thereof

Details Compounds having lectin properties and biological uses thereof Compounds having lectin properties and biological uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C12N 5/071 (2010.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2237495

Nucleotide sequences capable of coding for polypeptides having lectin properties and the corresponding sarcolectin-type polypeptides, and therapeutical uses thereof, are disclosed. In particular, the use of sarcolectin-type polypeptides for stimulating immunity, optionally in combination with interferon or butyroids, is disclosed. The use of specific inhibitors or antagonist peptides enables sarcolectin production to be opposed. Antibodies to said peptides are suitable for diagnostic and therapeutical use.

L'invention concerne des séquences de nucléotides capables de coder pour des polypeptides possédant des propriétés lectiniques et les polypeptides correspondants du type des sarcolectines en leurs applications en thérapeutique. Elle vise notamment l'utilisation des polypeptides du type des sarcolectines pour stimuler l'immunité, le cas échéant en association avec l'interféron ou des butyroïdes. L'utilisation d'inhibiteurs spécifiques ou peptides antagonistes, permet de s'opposer aux productions constitutives de SCL. Les anticorps dirigés contre lesdits peptides sont utilisables en diagnostic et en thérapeutique.

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