C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/16 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/4025 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01)
Patent
CA 2511856
The invention provides a compound of formula (I), wherein in the formula X, R1, R2 and R3 are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as a prolyl oligopeptidase inhibitor. The compounds of formula (I) can be used for the treatment of diseases or conditions where prolyl oligopeptidase inhibitors are indicated to be effective, for example for the treatment of neurodegenerative diseases, such as Alzheimer's disease and senile dementia
L'invention concerne un composé de formule (I), dans laquelle X, R¿1?, R¿2? et R¿3? sont tels que définis dans la revendication 1, ou un sel ou un ester pharmaceutiquement acceptable dudit composé, utile en tant qu'inhibiteur de la prolyl-oligopeptidase. Les composés de formule (I) peuvent être utilisés pour le traitement de maladies ou d'états où les inhibiteurs de la prolyl-oligopeptidase sont considérés efficaces, par exemple pour le traitement des maladies neurodégénératives, telles que la maladie d'Alzheimer et la démence sénile.
Christiaans Johannes
Forsberg Markus
Gynther Jukka
Jarho Elina
Jarvinen Tomi
Orion Corporation
Robic
LandOfFree
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